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Manchester Institute for Collaborative Research on Ageing

Scientists uncover the structure of tau filaments from Alzheimer's disease

6 July 2017

A study published this week in Nature uncovers the structure of tau filaments from Alzheimer's disease.

Researchers at the MRC Laboratory of Molecular Biology (LMB) have, for the first time, revealed the atomic structures of one of the two types of the abnormal filaments which lead to Alzheimer's disease. Understanding the structures of these filaments will be key in developing drugs to prevent their formation.

The researchers believe the structures they have uncovered could also suggest how tau protein may form different filaments in other neurodegenerative diseases. For further detail please see the Medical Research Councils article on this groundbreaking research:

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